Abstract:
Alafia barteri (Apocynaceae) is a climbing shrub having white or pink flowers. Traditionally, it has been
used to treat diseases like malaria, sickle cell anemia, and eye infections. This research is focused on
investigating the antioxidant and anti-arthritic activities of the aqueous and ethanol leaf and root extract of
Alafia barteri plant in vitro. In-vitro antioxidant methods used were 2, 2 -diphenyl-1-picrylhydrazyl assay,
reducing power activity and hydrogen peroxide scavenging assay while the anti-arthritic activity was
studied using the assay method of protein denaturation. Results revealed that aqueous and ethanol root
extracts scavenge free radicals, thus inhibiting damage caused by oxidative stress in arthritis while the
ethanol extracts of both the leaf and roots had good anti-arthritic activities as seen in its ability to decrease
protein denaturation
